Why Parkinson's

We believe in clinical evidence, we provide reliable treatments, we use safe technology.

I'm PINE, are you fine?

Parkinson's disease(PD) is currently the fastest-growing neurodegenerative disease in the world, characterized by a range of motor and non-motor symptoms, still without a cure. It typically begins between the ages of 55 and 65, affecting about 1-1.5% of the population over 65 worldwide. In Korea, approximately 150 thousand individuals are affected, and globally, the number exceeds 10 million.

Non-pharmacological treatments for PD are as necessary as pharmacological treatments but are currently not sufficiently provided. This is because there are not enough medical institutions that offer proper non-pharmacological treatments, most patients have mobility challenges to visit hospital, and there is the cost issue for in-person treatment.

Research

Our clinical studies ensure the need for and the adherence to digital therapy among patients with PD

Our neurologists and researchers have published studies on telemedicine and digital therapeutics in SCI-indexed journals on PD.

Products

PINE aims to create a "Virtual Parkinson's Hospital" that provides digital PD treatments on a single platform.

AI-powered digital therapeutics have the potential to enhance non-pharmacological home treatment more effectively for speech-language, exercise, and psychological issues in individuals living with PD.

Software as a Medical Device to improve Speech-Langauge disorders in PD

PINE SPEECH^®

PINE SPEECH^® is a smartphone software medical device that provides personalized treatment by evaluating the speech function of Parkinson's disease patients using a patient-led treatment system.

PINE SPEECH^® is intended to be a Class 2 medical device approved by a regulatory body with proven medical effectiveness and safety, and used by patients at home after prescription from a doctor at hospital. The treatment results are provided to the doctor.

A patient-tailored digital Speech-Language Therapy (SLT) protocol, consisting of treatment for breathing, oral motor, intensity, pitch, and pronunciation.

Speech AI evaluates the patient's voice during the treatment process to provide real-time feedback, and an AI medical assistant will improve digital treatment adherence.

Mobile App UI/UX was developed complying with digital accessibility for the elderly individuals with PD.

Software as a Medical Device to improve Speech-Langauge disorders in PD

PINE SPEECH^®

PINE SPEECH^® is a smartphone software medical device that provides personalized treatment by evaluating the speech function of Parkinson's disease patients using a patient-led treatment system.

A patient-tailored digital Speech-Language Therapy (SLT) protocol, consisting of treatment for breathing, oral motor, intensity, pitch, and pronunciation.

Speech AI evaluates the patient's voice during the treatment process to provide real-time feedback, and an AI medical assistant will improve digital treatment adherence.

Mobile App UI/UX was developed complying with digital accessibility for the elderly individuals with PD.

Software as a Medical Device to improve Exercise Rehabilitation in PD

PINE BODY^®

PINE BODY^® is a smartphone software medical device that provides personalized exercise programs by evaluating the patient's symptoms, severity, and daily condition to popularize exercise rehabilitation, which is the foundation of nonpharmacological treatment for degenerative neurological diseases.

PINE BODY^® is intended to be a Class 2 medical device approved by a regulatory body with proven medical effectiveness and safety.

Depending on the patient's symptoms and severity, a rehabilitation exercise program is provided that includes coordination, aerobic, strength training, and mobility-enhancing exercises.

AI analyzes the patient's exercise movements to provide real-time feedback, and aggregates the day's exercise performance to boost motivation for treatment.

The mobile app UI/UX make maximum use of visual and auditory cues to ensure easy use for elderly users.

Software as a Medical Device to improve Exercise Rehabilitation in PD

PINE BODY^®

PINE BODY^® is intended to be a Class 2 medical device approved by a regulatory body with proven medical effectiveness and safety.

Depending on the patient's symptoms and severity, a rehabilitation exercise program is provided that includes coordination, aerobic, strength training, and mobility-enhancing exercises.

AI analyzes the patient's exercise movements to provide real-time feedback, and aggregates the day's exercise performance to boost motivation for treatment.

The mobile app UI/UX make maximum use of visual and auditory cues to ensure easy use for elderly users.

Leadership

PINE is a digital therapeutics company co-founded by a professor of neurology at Seoul National University Hospital and a former C-level at large platforms and strategic consulting firm.

CEO & Co-Founder

Han-Joon Kim, MD, PhD

Seoul National University, College of Medicine, PhD (Neuroscience)

Professor at Seoul National University, College of Medicine
and Seoul National University Hospital (Neurology)

Medical Director at Movement Disorders Center
at Seoul National University Hospital

Secretary of the Asian-Oceanean Secion of International Parkinson's Disease Society

CTO & Co-Founder

Young-Ho Seo, MS in Eng.

Seoul National University, School of Engineering, MS (Industrial Eng.)

Chief Technology Officer at Culture Commerce, YES24.com

Chief Technology Officer at English Edutech, Creverse

Chief Operation Officer at Job Portal, AlbaParadise

Director Consultant at SK Corp. Valtech Consulting

Medical Advisor

Woongwoo Lee, MD, PhD

Seoul National University, College of Medicine, PhD (Neurology)

Professor at Nowon Eulji Medical Center (Neurology)

Jin-Woo Park, MD, PhD

Seoul National University, College of Medicine, PhD (Rehabilitation)

Professor at Donguk University Ilsan Hospital (Rehabilitation)

Minsoo Byen, MD, PhD

Seoul National University, College of Medicine, PhD (Neurology)

Professor at Seoul National University Hospital (Neurology)

Youngeun Kim, MD, PhD

Seoul National University, College of Medicine, PhD (Neurology)

Professor at Hallym University Hospital (Neurology)

Company

PINE has demonstrated its technological capabilities and business viability.

History

2026

06 Released PD exercise rehabilitation digital therapeutics,
PINE BODY^® v1.0

03 Korea MFDS approval of PINE SPEECH^®
confirmatory clinical trial plan
2025

12 Obtained digital medical device
manufacturing license

11 Certification of Korea Manufacturing and
Quality System (KGMP) for medical device

05 Selected for DTx development project
sponsored by the Ministry of Science and ICT
(funding KRW 1 bln.)

04 Released PD speech-language digital therapeutics,
PINE SPEECH^® v1.0

01 PINE SPEECH^® feasibility study published on
Journal of Medical Internet Research (IF 6.0)
2024

12 Establishment of corporate research institute,
venture company certification

10 Selected for Deeptech TIPS project sponsored by
the Ministry of SMEs and Startups (funding KRW 1.5 bln.)

08 Seed funding round -
Medytox Venture Investment, HG Initiative

05 PINE digital health incorporated
2023

12 Feasibility testing for elderly 25 PD patients in
Seoul National University Hospital

09 Development of MVP for PD speech-language treatment
2022

10 Preliminary clinical study on
PD speech-language remote treatment

History

2026

06 Released PD exercise rehabilitation digital therapeutics, PINE BODY^® v1.0

03 Korea MFDS approval of PINE SPEECH^® confirmatory clinical trial plan

2025

12 Obtained digital medical device manufacturing license

11 Certification of Korea Manufacturing and Quality System (KGMP) for medical device

05 Selected for DTx development project sponsored by the Ministry of Science and ICT (funding KRW 1 bln.)

04 Released PD speech-language digital therapeutics, PINE SPEECH^® v1.0

01 PINE SPEECH^® feasibility study published on Journal of Medical Internet Research (IF 6.0)

2024

12 Establishment of corporate research institute, venture company certification

10 Selected for Deeptech TIPS project sponsored by the Ministry of SMEs and Startups (funding KRW 1.5 bln.)

08 Seed funding round - Medytox Venture Investment, HG Initiative

05 PINE digital health incorporated

2023

12 Feasibility testing for elderly 25 PD patients in Seoul National University Hospital

09 Development of MVP for PD speech-language treatment

2022

10 Preliminary clinical study on PD speech-language remote treatment

Media

KBS1, January 8, 2025

Parkinson's speech-language digital therapeutics on TV

"I Have Parkinson's disease" appeared on popular TV health program, 'The Secret of a Birth, Aging, Illness, and Death'

Professor Han-Joon Kim is treating a Parkinson's patient with speech-language disorder using a prototype mobile app.
A female patient who has difficulty communicating in daily life is using a digital therapy app to self-treat herself by practicing speaking long and loudly.

Korea Biomedical Review, March 5, 2025

Doctors develop DTx offering 'personalized voice therapy' for Parkinson's disease

Researchers at Seoul National University Hospital (SNUH) have developed a digital therapy device in the form of an app that allows Parkinson's disease patients to get customized voice therapy at home through their smartphones.

The hospital said Friday that a research team led by Professor Kim Han-joon of the Department of Neurology has developed a smartphone-based digital therapy device that allows patients with Parkinson's disease to receive voice therapy at home without visiting a hospital.

The app evaluates the patient's voice condition. It automatically provides training accordingly. The training consists of breathing exercises, oral exercises, voice loudness training, pitch training, and speaking training.

출처 : https://www.koreabiomed.com

Seoul Economic Daily, September 14, 2025

"AI-powered speech therapy for Parkinson's disease - a doctor and an engineer join forces"

A doctor and an engineer have taken on the challenge of treating Parkinson's disease by combining medicine and IT. They are co-CEOs Han-Joon Kim and Young-Ho Seo, who founded PINE digital health in June last year. Professor Kim, a neurologist at Seoul National University Hospital, has devoted 25 years to Parkinson's patient care and research, while CEO Seo developed AI services as a CTO and IT strategy consultant at large platform companies.

Their first achievement is PINE SPEECH, a software for treating speech-language disorders in Parkinson's patients. Once a patient installs the app after a doctor's prescription, they can receive treatment anytime, anywhere. At its core, AI analyzes the patient's vocalization to provide personalized training. In the 2023 clinical study at Seoul National University Hospital, it recorded a treatment adherence rate of over 90%, patient satisfaction of 75%, and a self-assessment improvement rate of 58%.

The company is also developing PINE BODY, which analyzes a patient's exercise movements with AI to provide tailored exercise programs. PINE digital health aims to build a platform that benefits not only patients and caregivers but also medical staff and hospitals, establishing digital therapeutics as a new paradigm for Parkinson's disease management.

Source : https://www.sedaily.com

BioTimes, March 30, 2026

PINE digital health receives approval for the confirmatory clinical trial plan of Parkinson's DTx 'PINE SPEECH'

PINE digital health has moved a step closer to commercializing its digital therapeutic (DTx) for improving speech-language disorders in Parkinson's disease patients.

The company announced on March 30 that PINE SPEECH®, currently under development, received final approval of its confirmatory clinical trial plan from the Ministry of Food and Drug Safety (MFDS). This approval is the stage that finally verifies the product's safety and efficacy, and is a key procedure for obtaining future medical device market authorization.

Based on this approval, the company plans to launch a multi-center confirmatory clinical trial involving five major university hospitals in Korea from the second quarter of 2026. PINE SPEECH® is a smartphone-based software as a medical device (SaMD) designed to let patients perform speech rehabilitation training with AI-personalized feedback in their daily environment.

In a 2023 study conducted at Seoul National University Hospital, it achieved positive results in key indicators such as treatment adherence, satisfaction, and self-assessment improvement, and was published in the Journal of Medical Internet Research.

Source : https://www.biotimes.co.kr

AI powered Digital Therapeutics for Parkinson's disease
INnovative Experience

Why Parkinson's

We believe in clinical evidence, we provide reliable treatments, we use safe technology.

Research

Our clinical studies ensure the need for and the adherence to digital therapy among patients with PD

Products

PINE aims to create a "Virtual Parkinson's Hospital" that provides digital PD treatments on a single platform.

Software as a Medical Device to improve Speech-Langauge disorders in PD

PINE SPEECH^®

Software as a Medical Device to improve Speech-Langauge disorders in PD

PINE SPEECH^®

Software as a Medical Device to improve Exercise Rehabilitation in PD

PINE BODY^®

Software as a Medical Device to improve Exercise Rehabilitation in PD

PINE BODY^®

Leadership

PINE is a digital therapeutics company co-founded by a professor of neurology at Seoul National University Hospital and a former C-level at large platforms and strategic consulting firm.

Han-Joon Kim, MD, PhD

Young-Ho Seo, MS in Eng.

Medical Advisor

Company

PINE has demonstrated its technological capabilities and business viability.

History

2026

2025

2024

2023

2022

History

2026

2025

2024

2023

2022

Partners

Media

PINE digital health Inc.

Why Parkinson's

We believe in clinical evidence, we provide reliable treatments, we use safe technology.

Research

Our clinical studies ensure the need for and the adherence to digital therapy among patients with PD

Products

PINE aims to create a "Virtual Parkinson's Hospital" that provides digital PD treatments on a single platform.

Software as a Medical Device to improve Speech-Langauge disorders in PD

PINE SPEECH®

Software as a Medical Device to improve Speech-Langauge disorders in PD

PINE SPEECH®

Software as a Medical Device to improve Exercise Rehabilitation in PD

PINE BODY®

Software as a Medical Device to improve Exercise Rehabilitation in PD

PINE BODY®

Leadership

PINE is a digital therapeutics company co-founded by a professor of neurology at Seoul National University Hospital and a former C-level at large platforms and strategic consulting firm.

Han-Joon Kim, MD, PhD

Young-Ho Seo, MS in Eng.

Medical Advisor

Company

PINE has demonstrated its technological capabilities and business viability.

History

2026

2025

2024

2023

2022

History

2026

2025

2024

2023

2022

Partners

Media

PINE digital health Inc.

PINE SPEECH^®

PINE SPEECH^®

PINE BODY^®

PINE BODY^®